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K/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21
1% patients compared with placebo of 4
Smiles: O=C(C1=CC(CC2=NNC(=O)C3=CC=CC=C23)=CC=C1F)N1CCNCC1
dog 100%) and Cmax (mouse 92
Pyrrolidino PAF C-16 35 hydrochloride K/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21Pyrrolidino PAF C 16 is a synthetic analog of PAF C 16 with hypotensive action . Platelet activating factor (PAF; C16), a phospholipid mediator of inflammation, is secreted by several cell types including arterial endothelial cells, and can activate polymorphonuclear leucocytes and monocytes via specific cell surface receptors. PAF also stimulates the production of active oxygen species by human monocyte derived macrophages. PAF have potent
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