MDK-3017 ustat 3)4)40(52)48-39(33-13-7-6-8-14-33)42(54)50-29-34(28-37(50)41(53)47-36-17-11-15-32-12-9-10-16-35(32)36)46-38(51)30-60-27-26-59-25-24-58-23-22-57-21-20-56-19-18-45/h9-10

3)4)40(52)48-39(33-13-7-6-8-14-33)42(54)50-29-34(28-37(50)41(53)47-36-17-11-15-32-12-9-10-16-35(32)36)46-38(51)30-60-27-26-59-25-24-58-23-22-57-21-20-56-19-18-45/h9-10

Hyun-Jin An

InChi: InChI=1S/C18H12N4O3/c23-22(24)16-11-10-15(17-18(16)21-25-20-17)19-14-9-5-4-8-13(14)12-6-2-1-3-7-12/h1-11

PubMed Central PMCID: PMC4463969

MDK-3017 ustat 3)4)40(52)48-39(33-13-7-6-8-14-33)42(54)50-29-34(28-37(50)41(53)47-36-17-11-15-32-12-9-10-16-35(32)36)46-38(51)30-60-27-26-59-25-24-58-23-22-57-21-20-56-19-18-45/h9-10MDK 3017 is a K Ras inhibitor, by binding to K Ras in a hydrophobic pocket that is occupied by Tyr 71 in the apo Ras crystal structure. Product information CAS Number: 84783 01 7 Molecular Weight: 207. 29 Formula: C11H13NOS Chemical Name: (2 Hydroxy phenyl) pyrrolidin 1 yl methanethione Smiles: OC1=CC=CC=C1C(=S)N1CCCC1 InChiKey: QIKLOVZAPGSYNO UHFFFAOYSA N InChi: InChI=1S C11H13NOS c13 10 6 2 1 5 9(10)11(14)12 7 3 4 8 12 h1 2,5 6,13H,3 4,7 8H2