Doxylamine succinate tirizine D4 dihydrochloride Smiles: CC(C)C1=CC2=C(C=C1)OC1=NC(N)=C(C=C1C2=O)C(O)=O

Smiles: CC(C)C1=CC2=C(C=C1)OC1=NC(N)=C(C=C1C2=O)C(O)=O

370586-05-3

Epub 2015 May 14

Shusterman S

Doxylamine succinate tirizine D4 dihydrochloride Smiles: CC(C)C1=CC2=C(C=C1)OC1=NC(N)=C(C=C1C2=O)C(O)=ODoxylamine Succinate is a pyridine histamine H1 antagonist with pronounced sedative properties. Doxylamine succinate competitively blocks the histamine H1 receptor and limits the typical allergic and anaphylactic responses, including bronchoconstriction, vasodilation, increased capillary permeability, and spasmodic contraction of gastrointestinal smooth muscle, caused by actions of histamine on bronchial and gastrointestinal smooth muscles, and on