L-873724 ressin acetate Measurement of proliferation following treatment

Measurement of proliferation following treatment with Larotrectinib (LOXO-101) demonstrates a dose-dependent inhibition of cell proliferation in all three cell lines

for 22 days) has antiarthritic activity

5-dihydroxypentan-3-yl)amino]-8-methyl-7H

4-Di-O-caffeoylquinic acid

L-873724 ressin acetate Measurement of proliferation following treatmentL 873724 is a potent, orally bioavailable, selective and reversible non basic cathepsin K inhibitor, with IC50s of 0. 2, 178, 264, and 5239 nM for cathepsin K, cathepsin S, cathepsin L, cathepsin B, respectively. L 873724 also exhibits an IC50 of 0. 5 nM for rabbit cathepsin K. L 873724 inhibits bone resorption. Product information CAS Number: 603139 12 4 Molecular Weight: 481. 53 Formula: C23H26F3N3O3S Chemical Name: (2S) N (cyanomethyl) 4 methyl 2