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Formula: C5H21N2O7PS
is a chemical probe for PRMT5
CRA-026440 at 25 and 50 mg/kg given qdx3 per week significantly inhibits tumor growth at 40% (P<0
InChi: InChI=1S/C30H50O2/c1-25(2)13-14-27(5)15-16-29(7)19(20(27)17-25)9-10-23-28(6)18-21(31)24(32)26(3
Fenobam Catalog No.:M20651-C Formula: C5H21N2O7PSFenobam is a selective, orally active, and brain penetrant mGluR5 antagonist acting at an allosteric modulatory site (Kds of 54 and 31 nM for rat and human recombinant mGlu5 receptors, respectively). Fenobam displays inverse agonist activity which blocks the mGlu5 receptor basal activity with an IC50 of 84 nM. Fenobam exerts anxiolytic activity. Product information CAS Number: 57653 26 6 Molecular Weight: 266. 68 Formula: C11H11ClN4O2 Chemical Name: 1
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