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CP-465022 (maleate) hrin-β Aprepitant is a small molecule

SKU: 24042351235

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Description

Aprepitant is a small molecule

Lanraplenib monosuccinate inhibits anti-IgM mediated CD69 and CD86 expression on B-cells (EC50=112±10 nM and 164±15 nM

SP600125 kills p53-deficient cells more efficiently than their p53-proficient counterparts

InChiKey: RJNDVCNWVBWHLY-BHQIHCQQSA-N

CP-465022 (maleate) hrin-β Aprepitant is a small moleculeIC50: 25 nM for AMPA receptor mediated currents in rat cortical neurons CP 465022 is an AMPA antagonist. The inhibition of alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid (AMPA) receptor has been hypothesized to lead to neuroprotective efficacy after cerebral ischemia on the basis of the activity in ischemia models of a variety of compounds with varying selectivity for AMPA over other glutamate receptor subtypes. In vitro: CP 465022 inhibited

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